Roessler lab                                                           QMlogo

Main menu: Home Research People EPR Publications OpportunitiesTeaching Contact

  1. N. le Breton, J. J. Wright, A.J.Y.J. Jones, E. Salvadori, H. R. Bridges, J. Hirst, M. M. Roessler*, 'Using EPR Hyperfine Spectroscopy to define the Proton-Coupled Electron Transfer Reaction at Fe-S cluster N2 in Respiratory Complex I', J. Am. Chem. Soc., 139 (45), 16319-16326, selected as Spotlight Article
  2. H. Adamson, M. Robinson, J. J. Wright, L. A. Flanagan, J. Walton, D. Elton, D. J. Gavaghan, A. M. Bond, M.M. Roessler, A. Parkin (2017), 'Re-tuning the Catalytic Bias and Overpotential of a [NiFe]-hydrogenase via a Single Amino Acid Exchange at the Electron Entry/exit site', J. Am. Chem. Soc., 139 (31), pp 10677-1068Abstract Image
  3. F. A. Armstrong*, R. M. Evans, S. V. Hexter, B. J. Murphy, M. M. Roessler, P. Wulff (2016), 'Guiding Principles of Hydrogenase Catalysis Instigated and Clarified by Protein Film Electrochemistry', Acc. Chem. Res. 49 (5), pp 884-892    ACR.gif
  4. J. J. Wright, E. Salvadori, H. R. Bridges, J. Hirst & M. M. Roessler* (2016), 'Small-volume potentiometric titrations: EPR investigations of Fe-S cluster N2 in mitochondrial complex I' J. Inorg. Biochem. 162, pp 201-206

    Image 1

  5. L. A. Flanagan, J. J. Wright, M. M. Roessler, J.W. Moir & A. Parkin (2016) 'Re-engineering a NiFe hydrogenase to increase the H2 production bias while maintaining native levels of O2 tolerance' Chem. Commun. 52, pp 9133-9136
    Graphical abstract: Re-engineering a NiFe hydrogenase to increase the H2 production bias while maintaining native levels of O2 tolerance
  6. J. Hirst* & M. M. Roessler* (2016) 'Energy conversion, redox catalysis and generation of reactive oxygen species by complex I' BBA Bioenergetics. 1857 (7), pp 872-883
  7. B.J. Murphy,R. Hidalgo, M.M. Roessler, R.M. Evans, P.A. Ash, W.K. Myers, K.A. Vincent, and F.A. Armstrong (2015)
    'Discovery of Dark pH-dependent H+ Migration in a [NiFe]-hydrogenase and Its Mechanistic Relevance: Mobilising the Hydrido Ligand of the Ni-C Intermediate' J. Am. Chem. Soc. 137 (26), pp 8484-8489 

    Abstract Image

  8. R.M. Evans, A. Parkin, M.M. Roessler, B.J. Murphy, H. Adamson, M.J. Lukey, F. Sargent, A. Volbeda, J.C. Fontecilla-Camps, and F.A. Armstrong (2013)
    'Principles of Sustained Enzymatic Hydrogen Oxidation in the Presence of Oxygen – The Crucial Influence of High Potential Fe–S Clusters in the Electron Relay of [NiFe]-Hydrogenases' J. Am. Chem. Soc. 135 (7), pp 2694–2707.


    Abstract Image


  9. M.M. Roessler, R.M. Evans, R.A. Davies, J. Harmer, and F.A. Armstrong (2012)
    'EPR Spectroscopic Studies of the Fe–S Clusters in the O2-Tolerant [NiFe]-Hydrogenase Hyd-1 from Escherichia coli and Characterization of the Unique [4Fe–3S] Cluster by HYSCORE' J. Am. Chem. Soc. 134 (37), pp 15581–15594.


    Abstract Image


  10. A. Volbeda, P. Amara, C. Darnault, J.-M. Mouesca, A. Parkin, M.M. Roessler, F.A. Armstrong, J. C Fontecilla-Camps (2012)
    'X-ray crystallographic and computational studies of the O2-tolerant [NiFe]-hydrogenase 1 from Escherichia coli' Proceedings of the National Academy of Sciences 109 (14), pp 5305–5310.



  11. A. Parkin, L. Bowman, M.M. Roessler, R.A. Davies, T. Palmer, F.A. Armstrong, and F. Sargent (2012)
    'How Salmonella oxidises H2 under aerobic conditions' FEBS letters 586 (5), 536-544.



  12. M.J. Lukey, M.M. Roessler, A. Parkin, R.M. Evans, R.A. Davies, O. Lenz, B. Friedrich, F. Sargent, and F.A. Armstrong (2011)
    'Oxygen-Tolerant [NiFe]-Hydrogenases: The Individual and Collective Importance of Supernumerary Cysteines at the Proximal Fe-S Cluster' J. Am. Chem. Soc. 133 (42), pp 16881–16892.


    Abstract Image


  13. C.Y. Lee, G.P. Stevenson, A. Parkin, M.M. Roessler, R.E. Baker, K. Gillow, D.J. Gavaghan, F.A. Armstrong, and A.M. Bond (2011)
    'Theoretical and experimental investigation of surface-confined two-center metalloproteins by large-amplitude Fourier transformed ac voltammetry' Journal of Electroanalytical Chemistry 656 (1), 293-303



  14. M.M. Roessler, M.S. King, A.J. Robinson, F.A. Armstrong, J. Harmer, and J. Hirst (2010)
    'Direct assignment of EPR spectra to structurally defined iron-sulfur clusters in complex I by double electron–electron resonance' Proceedings of the National Academy of Sciences 107 (5), 1930-1935



  15. M.J. Lukey, A. Parkin, M.M. Roessler, B.J. Murphy, J. Harmer, T. Palmer, F. Sargent, and F.A. Armstrong (2010)
    'How Escherichia coli is equipped to oxidize hydrogen under different redox conditions' Journal of Biological Chemistry 285 (6), 3928-3938.