Second year essays
1. The commentry on the recent release of the human genome
has made much of the estimate that it contains only 40,000 genes rather
than the previous estimate of 100,000. It has been claimed that this
makes it less likely that large amounts of our behaviour are biologically
controlled. First explain what we mean by hertitability, then go
on to use these ideas to assess the proposal that having only 40,000 genes
makes it less likely aspects of our behaviour are biologically controlled.
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Sources for understanding heritability
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Basic genetics / Daniel L. Hartl.
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A primer of population genetics / Daniel L. Hartl.
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Principles of population genetics / Daniel L.Hartl and Andrew G.Clark
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Sources regarding the human genome projects
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See Nature of Feb 15 2001. Available electronically here
2. What has the study of human mtDNA taught us
about the relative merits of the "Out of Africa" and "Multiregional" hypotheses
of human evolution
3. Find an article in a national newspaper that describes
some published biological research (from the last two months, say). Find
the original
scientific work and related papers. Write
an essay entitled "An evaluation of the scientific reporting on X by Y"
where Y is the journalist
and X is the subject. First present what the
newspaper article said. Then, from your reading of the scientific literature,
evaluate if the press
article was accurate, if it should have dealt
with other issues and if it could have been improved in any other way.
Final year essays
1. Pick two papers from the current research literature.
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Include photocopies of the abstracts with your essay.
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Predict how the fields described in those papers
will develop in the next ten years.
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Write your essay in the form of article as if you
were a New Scientist journalist writing in 2011. Your article should
show how the two fields of research which were different ten years previously
(in 2001) have now come together to produce an exciting new development.
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Make sure you look at an issue of New Scientist so
you can see the general style that you should be using.
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The subjects of your two papers should ideally
be quite different so that you can demonstrate your ability to synthesise
ideas.
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Do not chose the human genome or cancer research!!
2. Exam conditions essay:
What impact has the disagreement among scientists had on the public’s
perception of the safety of the MMR vaccine, and on the reliability of
expert opinion?
3. Look at this
article. Use your literature-searching skills to find other examples
where there may appear to be a conflict between the financial incentives
and the imparitiality of scientists. In your essay, present these
examples, and also realistic suggestions for how the problem could be overcome.
Not this semester
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Where does the funding for the school of biological
sciences come from.
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Post-graduate students grants and their consumables
costs
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Post-doctoral researchers salaries and their consumables
costs
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Lecturers wages and the cost of their research.
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The cost of technical and support staff
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The cost of maintaining the building and central
administration.
You should include reference to Hefce, the research
councils, charities, self-funding students, undergraduate fees.
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Read the article that I gave you from the Evening
Standard about the "Baby Created to Save Sister".
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Write an essay to answer the question "What laws
and regulatory authorities exist in the UK to regulate such events, and
what challenges to the current system do you anticipate from recent developments
in genetics"
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You may find interesting leads in Thompson et
al 1998 Science 282:1145-1147. You could start here: online
text
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Read about the Warnock report and current UK law.
Try starting here: current
UK law
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Review the possible risks arising out of the development
of GMOs (genetically modified organisms). Include both political (eg Monsanto's
monopoly position), ecological and genetic.
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Use your literature research skills to find and evaluate
the evidence for the seriousness of these risks.
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Write an essay entitled "GMOs the risks and the evidence",
finishing with your own opinions.
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Useful starting points
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Deaths from tryptophan contamination Available
here
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The Friends of the Earth web site is HERE
but remember they are a campaigning organisation not a peer reviewed scientific
journal. You need to go back to other sources to cross-check what they
say.
Not this semester
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Look at the following book, which is in the Short
Loan Collection:
Evolution / edited by Mark Ridley. Oxford : Oxford
University Press, 1997.
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Chose one of the papers in it.
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Use the literature searching methods you have just
been taught in the Library exercise to find out how this area has changed
since the paper was written.
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Write an essay using the style set out here: Click
here for instructions
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The title should be "Developments in X since the
work by Y in date" where "X" is the subject matter in question and "Y"
is the author(s) and "date" is the date of the paper reproduced in Ridley's
book
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Read the article that I supplied you with by Prof.
Lichtenstein from the Guardian newspaper. Use your literature searching
skills to find the scientific evidence that the article is based on. Hint
try finding reviews by Crow J* and Barton NH on this subject. Write a critique
on the piece. I.e.
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Are his facts right?
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What is his argument, do you agree that it is a logical
use of the data? Have others come to different conclusions?
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What is the sociological context of the article.
Why is he writing it ? What does he hope to acheive?
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What would your interpretation of the data be. Why
is it better, (or the same).
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Make sure your essay could be understood by one of
your colleagues, and that you cite all of your sources, including internet
sites. (To see how to do that look at the essay advice on the previous
page)
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Find an article in a national newspaper that describes
some published biological research (from the last two months, say). Find
the original scientific work and related papers. Write an essay entitled
"An evaluation of the scientific reporting on X by Y" where Y is the journalist
and X is the subject. First present what the newspaper article said. Then,
from your reading of the scientific literature, evaluate if the press article
was accurate, if it should have dealt with other issues and if it could
have been improved in any other way.