QMUL People: Richard Hooper

This webpage is a collection of resources relating to my research. Click here for my official staff web-page.


My current research interests centre on innovations in the design of clinical trials, particularly stepped wedge and other extensions to cluster randomized trials.


Follow the links below for some of my publications in this area. (Some journal websites may require you or your institution to have a subscription. If you would like a PDF copy of any of these articles please email me).

Hooper R, Knowles C. Improving the efficiency of individually randomized clinical trials by staggering the introduction of the intervention. Stat Med 2018;DOI:10.1002/sim.7959

Hooper R, Forbes A, Hemming K, Takeda A, Beresford L. Analysis of cluster randomised trials with an assessment of outcome at baseline. BMJ 2018;360:k1121

Kasza J, Hemming K, Hooper R, Matthews JNS, Forbes AB. Impact of non-uniform correlation structure on sample size and power in multiple-period cluster randomised trials. Stat Methods Med Res 2017;DOI:10.1177/0962280217734981

Hooper R, Teerenstra S, de Hoop E, Eldridge E. Sample size calculation for stepped wedge and other longitudinal cluster randomised trials. Stat Med 2016;35(26):4718-4728

Hooper R, Bourke L. Cluster randomised trials with repeated cross sections: alternatives to parallel group designs. BMJ 2015;350:h2925

Hooper R, Bourke L. The dog-leg: an alternative to a cross-over design for pragmatic clinical trials in relatively stable populations. Int J Epidemiol 2014;43(3):930-936


Some of my conference presentations are also included below:

The shape of clinical trials. William Harvey Day 2018

Optimal incomplete stepped wedge designs in continuous time. International Society for Clinical Biostatistics / Australian Statistical Conference 2018

Sample size for stepped wedge trials. Royal Statistical Society Conference 2018

Analysing cluster randomised trials with an assessment of outcome at baseline - an update. Current developments in cluster randomised trials and stepped wedge designs 2017

Why clinical trials are like bicycles. Pride and Pragmatism: celebrating 50 years of the pragmatic trial 2017

Trimming the fat from stepped wedge trials: an algorithmic search for the trial design requiring the fewest participants. Society for Clinical Trials / International Clinical Trials Methodology Joint Conference 2017

Choosing a two-stage design for a cluster randomised trial with one-way cross-over: the benefits of incompleteness. International Society for Clinical Biostatistics Conference 2016

Sample size calculation for longitudinal cluster randomised trials: a unified framework for closed cohort and repeated cross-section designs. First International Conference on Stepped Wedge Design 2016

Analysing cluster randomised trials with a baseline assessment of outcome. Current developments in cluster randomised trials and stepped wedge designs 2015

Stepped wedge designs for individually randomised trials with waiting list controls. Current developments in cluster randomised trials and stepped wedge designs 2015


To visit the website for my versatile sample size calculation software, SimSam, click here.