Goldup Group Publications

1. Unusual Mechanistic Course of Some NHC-Mediated Transesterifications

S. M. Goldup, T. Papalia, A. M. Z. Slawin, L. Pignataro
Org. Lett. 2009, 11, 1643.

15. Sequence-Specific Peptide Synthesis by an Artificial Small-Molecule Machine

B. Lewandowski, G. De Bo, J. W. Ward, M. Papmeyer, S. Kuschel, M. J. Aldegunde, P. M. E. Gramlich, D. Heckmann, S. M. Goldup, D. M. D’Souza, A. E. Fernandes, D. A. Leigh
Science 2013, 339, 189.

Highlighted in multiple news sources including Nature News, Chemical and Engineering News, Chemistry World, the BBC and the New Scientist.

For a cartoon video of the machine in action click here.

14. A Three-Compartment Chemically-Driven Molecular Information Ratchet

A. Carlone, S. M. Goldup, N. Lebrasseur, D. A. Leigh, A. Wilson
J. Am. Chem. Soc. 2012, 134, 8321.

Highlighted in by Eva Gabel in "Spotlight on Recent JACS Papers" (J. Am. Chem. Soc. 2012, 134, 9830.)

13. Active-Metal Template Synthesis of a Molecular Trefoil Knot

P. E. Barran, H. L. Cole, S. M. Goldup, D. A. Leigh, P. R. McGonigal, M. D. Symes, J. Wu, M. Zengerle
Angew. Chem. Int. Ed. 2011, 50, 12280.

Angewandte Very Important Paper and Cover article

Highlighted by Frédéric Coutrot in Angew. Chem. Int. Ed. 2012, DOI: 10.1002/anie.201107112

12. Ligand-Assisted Nickel-Catalysed sp3-sp3 Homocoupling of Unactivated Alkyl Bromides and its Application to the Active Template Synthesis of Rotaxanes

S. M. Goldup, D. A. Leigh, R. T. McBurney, P. R. McGonigal, A. Plant
Chem. Sci. 2010, 1, 383.

11. An Unusual Nickel−Copper-Mediated Alkyne Homocoupling Reaction for the Active-Template Synthesis of [2]Rotaxanes

J. D. Crowley, S. M. Goldup, N. G. Gowans, D. A. Leigh, V. E. Ronaldson, A. M. Z. Slawin
J. Am. Chem. Soc. 2010, 132, 6243.

10. Two Axles Threaded Using a Single Template Site: Active Metal Template Macrobicyclic [3]Rotaxanes

S. M. Goldup, D. A. Leigh, P. M. McGonnigal, V. E. Ronaldson, A. M. Z. Slawin
J. Am. Chem. Soc. 2010, 132, 315.

Highlighted in Synfacts 2010, 3, 301.

9. Active Metal Template Synthesis of [2]Catenanes

S. M. Goldup, D. A. Leigh, T. Long, P. R. McGonigal, M. D. Symes, J. Wu
J. Am. Chem. Soc. 2009, 131, 15924.

8. Active Metal Template Synthesis of Rotaxanes, Catenanes and Molecular Shuttles

J. D. Crowley, S. M. Goldup, A.-L. Lee, D. A. Leigh, R. T. McBurney
Chem. Soc. Rev. 2009, 1530.

7. Gold(I) Catenane and Rotaxane Synthesis

S. M. Goldup, D. A. Leigh, P. J. Lusby, R. T. McBurney, A. M. Z. Slawin
Angew. Chem. Int. Ed. 2008, 47, 6999.

Cover article

6. Cadiot-Chodkiewicz Active Template Synthesis of Rotaxanes and Switchable Molecular Shuttles with Weak Intercomponent Interactions

J. Berná, S. M. Goldup, A.-L. Lee, D. A. Leigh, M. D. Symes, G. Teobaldi, F. Zerbeto
Angew Chem. Int. Ed. 2008, 47, 4392.

5. Active Template Synthesis of Rotaxanes and Molecular Shuttles with Switchable Dynamics via Four-Component Pd(II)-Catalyzed Michael Additions

S. M. Goldup, D. A. Leigh, P. J. Lusby, R. T. McBurney
Angew. Chem. Int. Ed. 2008, 47, 3381.

4. A Chemically-Driven Molecular Information Ratchet

M. Alvarez-Pérez, S. M. Goldup, D. A. Leigh, A. M. Z. Slawin
J. Am. Chem. Soc. 2008, 130, 1836.

Highlighted in Science News, 2008, 173, 120.

3. A Catalytic ‘Active-Metal’ Template Strategy to [2]Rotaxanes, [3]Rotaxanes and Molecular Shuttles and Some Observations on the Mechanism of the Cu(I)-Catalyzed Azide-Alkyne 1,3-Cycloaddition

V. Aucagne, J. Berná, J. D. Crowley, S. M. Goldup, K. D. Hänni, D. A. Leigh, P. J. Lusby, V. E. Ronaldson, A. M. Z. Slawin, A. Viterisi, D. B. Walker
J. Am. Chem. Soc. 2007, 129, 11950.

2. A Catalytic Palladium Active-Metal Template Pathway to [2]Rotaxanes

J. Berna, J. D. Crowley, S. M. Goldup, K. D. Hänni, A.-L. Lee, D. A. Leigh
Angew. Chem. Int. Ed., 2007, 46, 5709.

Highlighted in Synfacts, 2007, 11, 1158.

1. A Simple, Short, and Flexible Synthesis of Viridiofungin Derivatives

S. M. Goldup, C. J. Pilkington, A. J. P. White, A. Burton, A. G. M. Barrett
J. Org. Chem. 2006, 71, 6185.